Once again, "for your friend"....lol.....mRNA technology has been around for 30 YEARS!
Its not new or untested............Its been used before with great results. As with ANY drug, it doesn't agree with anyone.
As far as pumping people full of shots, when you're dealing with a pandemic, the goal is immunity. Whatever it takes!
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[HEADING=2]Those Virus Sequences That Were Suddenly Deleted? They're Back[/HEADING]
Carl Zimmer
Sat, July 31, 2021, 7:15 AM
*A batch of early coronavirus data that went missing for a year has emerged from hiding.
In June, an American scientist discovered that more than 200 genetic sequences from COVID-19 patient samples isolated in China early in the pandemic had puzzlingly been removed from an online database. With some digital sleuthing, Jesse Bloom, a virus expert at the Fred Hutchinson Cancer Center in Seattle, managed to track down 13 of the sequences on Google Cloud.
When Bloom shared his experience in a report posted online, he wrote that it “seems likely that the sequences were deleted to obscure their existence.”
But now an odd explanation has emerged, stemming from an editorial oversight by a scientific journal. And the sequences have been uploaded into a different database, overseen by the Chinese government.
The story began in early 2020, when researchers at Wuhan University investigated a new way to test for the deadly coronavirus sweeping the country. They sequenced a short stretch of genetic material from virus samples taken from 34 patients at a Wuhan hospital.
The researchers posted their findings online in March 2020. That month, they also uploaded the sequences to an online database called the Sequence Read Archive, which is maintained by the National Institutes of Health, and submitted a paper describing their results to a scientific journal called Small. The paper was published in June 2020.
Bloom became aware of the Wuhan sequences this spring while researching the origin of COVID-19. Reading a May 2020 review about early genetic sequences of coronaviruses, he came across a spreadsheet that noted their presence in the Sequence Read Archive.
But Bloom could not find them in the database. He emailed the Chinese scientists on June 6 to ask where the data went but did not get a response. On June 22, he posted his report, which was covered by The New York Times and other media outlets.
At the time, a spokesperson for the NIH said that the authors of the study had requested in June 2020 that the sequences be withdrawn from the database. The authors informed the agency that the sequences were being updated and would be added to a different database. (The authors did not respond to inquiries from the Times.)
But a year later, Bloom could not find the sequences on any database.
On July 5, more than a year after the researchers withdrew the sequences from the Sequence Read Archive and two weeks after Bloom’s report was published online, the sequences were quietly uploaded to a database maintained by China National Center for Bioinformation by Ben Hu, a researcher at Wuhan University and a co-author of the Small paper.
On July 21, the disappearance of the sequences was brought up during a news conference in Beijing, where Chinese officials rejected claims that the pandemic started as a lab leak.
According to a translation of the news conference by a journalist at the state-controlled Xinhua News Agency, the vice minister of China’s National Health Commission, Dr. Zeng Yixin, said that the trouble arose when editors at Small deleted a paragraph in which the scientists described the sequences in the Sequence Read Archive.
“Therefore, the researchers thought it was no longer necessary to store the data in the NCBI database,” Zeng said, referring to the Sequence Read Archive, which is run by the NIH.
An editor at Small, which specializes in science at the micro and nano scale and is based in Germany, confirmed his account. “The data availability statement was mistakenly deleted,” the editor, Plamena Dogandzhiyski, wrote in an email. “We will issue a correction very shortly, which will clarify the error and include a link to the depository where the data is now hosted.”
The journal posted a formal correction to that effect on Thursday.
It is not clear why the authors did not mention the journal’s error when they requested that the sequences be removed from the Sequence Read Archive, or why they told the NIH that the sequences were being updated. Nor is it clear why they waited a year to upload them to another database. Hu did not respond to an email asking for comment.
Bloom could not offer an explanation for the conflicting accounts, either. “I’m not in a position to adjudicate among them,” he said in an interview.
On their own, these sequences can’t resolve the open questions about how the pandemic originated, whether through a contact with a wild animal, a leak from a lab or some other route.
In their initial reports, the Wuhan researchers wrote that they extracted genetic material from “samples from outpatients with suspected COVID-19 early in the epidemic.” But the entries in the Chinese database now indicate that they were taken from Renmin Hospital of Wuhan University on Jan. 30 — almost two months after the earliest reports of COVID-19 in China.
While the disappearance of the sequences appears to be the result of an editorial error, Bloom felt that it was still worthwhile looking for other sequences of coronaviruses that might be lurking online. “It definitely means we should keep looking,” he said.*
© 2021 The New York Times Company
terrific.......
[URL unfurl="true"]https://www.yahoo.com/news/vaccine-resistant-lambda-variant-us-193100413.html[/URL]
[URL unfurl="true"]https://www.yahoo.com/news/millions-coronavirus-vaccine-doses-around-155518313.html[/URL]
Question for our resident scientist. If the Lambda strain is not responding well to the vaccine already in your honest opinion how many more strains until it is totally ineffective?
just to clarify I am talking about current vaccines already out. Not those in phase 3 trials, etc.
No idea Ben. The spike protein binding site has to stay relatively conserved or the bug will lose infectivity. No clue as to how much is too much.
Great question!
My best guess is the vaccine composition might change similar to the annual flu shot depending on the dominant strains.
As long as the spike protein is the main driver of symptoms and illness, the current vax will work.
Some interesting data starting to come out specifically addressing the high incidence of infection and death in the Black comminities.
To explain in english, every ethnic group has HLA antibodies that are specific and prevalent in that group. For Blacks, the specific HLA antibody is B53.
Seems B53 was very common in those who had bad to fatal experiences.
So those of you who feel you were exposed but didnt get sick, chances are you had the wrong (or right depending on how you look at it) antibodies that triggered the fatal immune response.
More and more data is coming out INCLUDING the Moderna vs Pfizer debate
and
Hopefully more on the booster shot. Saw CVS offering Moderna booster shots but it hasnt yet been approved. Pfizer has has been approved for booster.
interesting read - your mileage may vary
[URL unfurl="true"]https://www.yahoo.com/finance/news/its-game-over-its-m-rna-or-nothing-expert-on-future-of-vaccines-200508222.html[/URL]
mRNA technology has proven to be a big success HOWEVER Im very leary of dismissing the "old" technology in favor of the new kid. Still a place for "live" vaccines especially in children.
Is this a business decision? of course it is!
Will it sustain its effectiveness in the longer term? That remains to be seen. Right now, there is no argument. IMHO, Its effectiveness outweighs the potential negatives.
interesting read - your mileage may vary
[URL unfurl="true"]https://www.yahoo.com/finance/news/its-game-over-its-m-rna-or-nothing-expert-on-future-of-vaccines-200508222.html[/URL]
Typical limited prose from folks who can’t see the forest from the trees. YES mRNA is a powerful new tool, but like every tool there’s a right and wrong time to use it. Linear, non-conformation Ab targets, like the COVID spike protein has, are great mRNA use. For complex, confirmational, and/or membrane-bound protein targets, mRNA will have short comings. Break out the attenuated virus vaccines!!
Please take your thoughtful "COVID Party Invitation" to the other COVID thread where it belongs...
[SIZE=1][COLOR=rgb(239, 239, 239)]Belongs where ever I chose to put it
You chose to delete it I guess that’s fine
but I’ll put things where I please[/COLOR][/SIZE]
And I’ll edit what doesn’t belong in this thread.
- According to the University of Miami's Miller School of Medicine, a study of 45 men showed that Pfizer and Moderna mRNA vaccines appear safe for the male reproductive system - The study looked at sperm characteristics, like quantity and movement, before and after vaccination, and researchers found no significant changes after the vaccine, the CDC said.
We test just 45 men and from that, we determine that they "appear safe" If I were concerned about that I probably wouldn't have taken the jab.
My 29-year-old pointed this out to me. He and most people of childbearing age need more assurances than just "appear safe." And the truth is only time will tell. right?
It's like the year they made 27 intercepts to determine the recreational catch of porgies!
One more thing. I've been reading about aborted fetal cell lines that are used in the development of the vaccines. Granted they come from abortions that occurred in the Netherlands in the '70s and '80s. So when my son says "it has aborted cell lines it" he's right. I guess?
Yes
[SIZE=1][COLOR=rgb(239, 239, 239)]Belongs where ever I chose to put it
You chose to delete it I guess that’s fine
but I’ll put things where I please[/COLOR][/SIZE]
And I’ll edit what doesn’t belong in this thread.
have at it
You’ve got nothing better to do anyway
- According to the University of Miami's Miller School of Medicine, a study of 45 men showed that Pfizer and Moderna mRNA vaccines appear safe for the male reproductive system - The study looked at sperm characteristics, like quantity and movement, before and after vaccination, and researchers found no significant changes after the vaccine, the CDC said.
We test just 45 men and from that, we determine that they "appear safe" If I were concerned about that I probably wouldn't have taken the jab.
My 29-year-old pointed this out to me. He and most people of childbearing age need more assurances than just "appear safe." And the truth is only time will tell. right?
It's like the year they made 27 intercepts to determine the recreational catch of porgies!
One more thing. I've been reading about aborted fetal cell lines that are used in the development of the vaccines. Granted they come from abortions that occurred in the Netherlands in the '70s and '80s. So when my son says "it has aborted cell lines it" he's right. I guess?
George: The mRNA vaccines do NOT have any fetal materials in them. The nanoparticles that contain the mRNA, and the mRNA itself, are both synthesized. These vaccines contain NO cellular materials.
I can't speak for the J&J vaccine or the AstraZeneca ones, as I'm not sure about the lineage of the cells used
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