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The COVID-19 Science and Medicine Question Thread

70,573 views·762 replies·by Roccus7·First Post·Latest
TonySmjc
TonySmjcFREE2020#461

More drivel

Captain1,857 postsSince 2020
TonySmjc
TonySmjcFREE2020#462

More drivel

Captain1,857 postsSince 2020
Roccus7
Roccus7MODnoreaster.com2020#463

Party boats and charters too ?

Who knows?

Shall I go to heaven or a-fishing? - H. D. Thoreau
Veni. Vidi. Cepi. - with apologies to Gaius Julius Caesar
AdmiralOriginal Crew21,717 postsSince 2018
TonySmjc
TonySmjcFREE2020#464

Obviously you're bucking for a time out. Present some real DATA and you may post away. Since you've yet to provide anything from a scientific standpoint, feel free to post all conjecture and opinion on the other COVID thread.

BTW, how's the "numerical value" for your COVID-19 Antibody Test result you swore your doctor would get to you??? We're still waiting with baited breath...

Captain1,857 postsSince 2020
TonySmjc
TonySmjcFREE2020#465

Drivel and drool. You got some science to share, we're all ears. You got nothing, then take your soapbox to the other thread and pontificate away...

Captain1,857 postsSince 2020
pequa1
pequa1MODnoreaster.com2020#466

Saw a reference to the mumps, measles and rubella vaccine as possibly a help in warding off the china virus. What I could not find in the same reference was the recency of the MMR vaccine. Without regard to covid19, does one have to get subsequent vaccinations of the MMR similar to tetanus and the flu vaccine ? Regarding the two different "types" of covid vaccines, does either purport to last longer as a preventative ?

Every day is Saturday.
CommodoreOriginal Crew7,034 postsSince 2018
Roccus7
Roccus7MODnoreaster.com2020#467

The answer to your COVID specific questions is “Unknown at the present time”. Still on the learning curve and you asked questions that take time to answer. This highlights why a "normal" process takes years, as we may not know for years how long the immunity will last. They'll answer this by continuing to monitor clinical trial patients to see how long their antibodies continue to last.

Shall I go to heaven or a-fishing? - H. D. Thoreau
Veni. Vidi. Cepi. - with apologies to Gaius Julius Caesar
AdmiralOriginal Crew21,717 postsSince 2018
jpd
jpdMODnoreaster.com2020#468

My shocked face ?

[URL unfurl="true"]https://www.npr.org/2020/11/06/929078678/cdc-report-officials-knew-coronavirus-test-was-flawed-but-released-it-anyway[/URL]

A lawyer with his briefcase can steal more than a hundred men with guns- Mario Puzo
CommodoreOriginal Crew9,876 postsSince 2018
Roccus7
Roccus7MODnoreaster.com2020#469

My shocked face ?

[URL unfurl="true"]https://www.npr.org/2020/11/06/929078678/cdc-report-officials-knew-coronavirus-test-was-flawed-but-released-it-anyway[/URL]

Sad, but very true. It's easy to get a prototype assay to work and takes about 5% of a project time. There other 95% of time is spent shaking it out and making sure it actually works all the time and can be manufactured...

To be fair, an academic scientist wouldn't have a clue how to do this and this result is proof of that.

Shall I go to heaven or a-fishing? - H. D. Thoreau
Veni. Vidi. Cepi. - with apologies to Gaius Julius Caesar
AdmiralOriginal Crew21,717 postsSince 2018
Matts
MattsFREE2020#470

My shocked face ?

[URL unfurl="true"]https://www.npr.org/2020/11/06/929078678/cdc-report-officials-knew-coronavirus-test-was-flawed-but-released-it-anyway[/URL]

Isn't this old news. I seem to recall months ago, during the era of "everyone who wants a test, can get a test," a report that the Federal Gov't rejected European test kits in favor of US sourced kits, but then those kits were flawed; or was that something else?

First MateOriginal Crew693 postsSince 2019
wader
waderFREE2020#471

[U]Question[/U]: How will you know when it's your turn to get the vaccine? Is there a plan in place for this? Will you be notified?

I tried looking that up but didn't really find anything concrete.

"Well, it's alright.
.............even if you're old and gray."
"Well, it's alright.
............you still got something to say."
AdmiralOriginal Crew20,900 postsSince 2018
Roccus7
Roccus7MODnoreaster.com2020#472

[U]Question[/U]: How will you know when it's your turn to get the vaccine? Is there a plan in place for this? Will you be notified?

I tried looking that up but didn't really find anything concrete.

Each individual state is responsible for the organization of the vaccinations. Contact your State CDC to find out more.

Shall I go to heaven or a-fishing? - H. D. Thoreau
Veni. Vidi. Cepi. - with apologies to Gaius Julius Caesar
AdmiralOriginal Crew21,717 postsSince 2018
WhatKnot
WhatKnotFREE2020#473

The R&D and approval process on those vaccine was, to say the least, expedited. But what about the testing process, was it as rigorous and expansive as other vaccines were in the past?

Be Safe
CommodoreOriginal Crew12,915 postsSince 2019
Roccus7
Roccus7MODnoreaster.com2020#474

The R&D and approval process on those vaccine was, to say the least, expedited. But what about the testing process, was it as rigorous and expansive as other vaccines were in the past?

Pretty much so. The key here is parallel project tasks versus sequential. In a "normal" time line, you do each project phase in sequence so in case you find any surprises, your potential materials lost due to reformulations are minimized. Here, Pfizer & Moderna locked down their manufacturing early and made clinical trial materials, and Operation Warp Speed told them to go ahead to manufacture X doses of vaccine for distribution prior to the EUA acceptance. Had they had any "surprises", the US government was going to cover that financial loss.

Now we're seeing the offshoot from this "Damn the torpedoes, full steam ahead" process with AstrZeneca's misstep. They had an epic fail by getting the concentration of their active ingredient wrong, allowing for that unplanned "lower" initial vaccine dose. It seems fortuitous in that it appears to give a better immune response, but by not running your clinical trials according to the approved protocol, the trial is invalid. That's why were not hearing about an impending US submission from them, they are redoing their Phase III Clinicals with the appropriate protocol.

Finally, the Emergency Use Authorization allows for product to be release prior to post-clinical studies that are mandatory for a full FDA Approval. We're seeing some of the items that are usually answered, but not in this case. The fact that nobody can tell how long immunity lasts is because this is a real-time event and can't be predicted. Pfizer and Moderna continue to test immunity in their clinical subjects, but since clinicals were complete only a few months ago, and folks still have significant antibodies to the spike protein, all we know is that immunity "lasts" for few months. As time passes and testing continues, this immunity window will probably expand, but for how long nobody knows.

Shall I go to heaven or a-fishing? - H. D. Thoreau
Veni. Vidi. Cepi. - with apologies to Gaius Julius Caesar
AdmiralOriginal Crew21,717 postsSince 2018
WhatKnot
WhatKnotFREE2020#475

I feel better; sorta. But it’s the only game in town and I’m willing to give it a shot; pun intended.

Be Safe
CommodoreOriginal Crew12,915 postsSince 2019
movetheboat

[U]Question[/U]: How will you know when it's your turn to get the vaccine? Is there a plan in place for this? Will you be notified?

I tried looking that up but didn't really find anything concrete.

alphabetical order....by NYA screen name...hang in there

CommodoreOriginal Crew12,530 postsSince 2018
movetheboat

[HEADING=2]just wonderful eh?[/HEADING]
[HEADING=2][/HEADING]
[HEADING=2]London Begins Emergency Lockdown as U.K. Fights New Virus Strain[/HEADING]
By
[Tim Ross]('https://www.bloomberg.com/authors/ATA2uoEiDe0/tim-ross')
and
[Eddie Spence]('https://www.bloomberg.com/authors/AUJMUap-1RE/eddie-spence')
December 19, 2020, 11:19 AM EST Updated on December 19, 2020, 7:04 PM EST

Bloomberg - Are you a robot?

CommodoreOriginal Crew12,530 postsSince 2018
Roccus7
Roccus7MODnoreaster.com2020#478

[HEADING=2]just wonderful eh?[/HEADING]
[HEADING=2][/HEADING]
[HEADING=2]London Begins Emergency Lockdown as U.K. Fights New Virus Strain[/HEADING]
By
[Tim Ross]('https://www.bloomberg.com/authors/ATA2uoEiDe0/tim-ross')
and
[Eddie Spence]('https://www.bloomberg.com/authors/AUJMUap-1RE/eddie-spence')
December 19, 2020, 11:19 AM EST Updated on December 19, 2020, 7:04 PM EST

[Bloomberg - Are you a robot?]('https://www.bloomberg.com/news/articles/2020-12-19/london-put-in-emergency-lockdown-as-u-k-fights-new-virus-strain')

Strain seems to be more contagious, although there is some scientific debate going on regarding this. Everyone agrees that it is NOT more virulent, thank goodness, and it is covered by the vaccines.

Shall I go to heaven or a-fishing? - H. D. Thoreau
Veni. Vidi. Cepi. - with apologies to Gaius Julius Caesar
AdmiralOriginal Crew21,717 postsSince 2018
M
MacksFREE2020#479

[U]Question[/U]: How will you know when it's your turn to get the vaccine? Is there a plan in place for this? Will you be notified?

I tried looking that up but didn't really find anything concrete.

My Doc thinks he'll have the Moderna vaccine in his office in the next month,he said this just a few days ago..

First MateOriginal Crew641 postsSince 2019
pequa1
pequa1MODnoreaster.com2020#480

I certainly hope that they continue to ship the Pfizer vaccine to the hospitals etc. with the super freezers and don't waste Moderna's on them and instead ship Moderna to the pharmacies and doctors with just regular refrigerators. But it is the gubmint behind this, isn't it.

Every day is Saturday.
CommodoreOriginal Crew7,034 postsSince 2018

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